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☆☆Funding: The authors declare that no funding sources were provided.
★Conflict of interest: The authors declare that they have no conflict of interest.
★★Author contributions: HB and SN conceived the study, and designed the trial. SN, HB, WB, RB, MHG, HB, and KB supervised the conduct of the trial and data collection. HB was the acupuncturist of the study. HB, NB, NF, and MAM undertook recruitment of patients and managed the data, including quality control. SN, HB, NB, and MHG performed statistical analysis and analyzed the data. SN drafted the manuscript. HB and NB revised the manuscript. SN takes the responsibility for the paper as a whole. This study was supported in part by the Tunisian Ministry of Scientific Research.