Use of dexmedetomidine to treat delirium primarily caused by cannabis

Published:October 10, 2016DOI:
      Dexmedetomidine is increasingly used to treat major withdrawal symptoms and hyperadrenergic crisis. We present 3 young adult cases of cannabis/drug-induced delirium unresponsive to traditional tranquilizer treatment but were responsive to dexmedetomidine as adjunct therapy. All cannabis metabolite urine concentrations were greater than 264 ng/mL upon presentation. Appropriate sedation was achieved within 5 hours in all 3 cases. Thus, dexmedetomidine, along with other tranquilizers, was effective in treating delirium due to cannabis/drug ingestion.
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