Abstract
We present a case of pyelonephritis following the extended andsolitary use of over-the-counter
phenazopyridine in a forty-year-oldfemale. The patient initially had uncomplicated
cystitis signs andsymptoms which partially resolved with phenazopyridine and therefore
she continued use. She presented to the emergency department with systemicsigns and
symptoms of acute pyelonephritis. As phenazopyridine is devoidof antibacterial properties
this allowed the lower urinary tractinfection to progress to acute pyelonephritis
requiring intravenousantibiotics. Better patient education may preclude this complication.
To read this article in full you will need to make a payment
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to The American Journal of Emergency MedicineAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Epidemiology of urinary tract infections: incidence, morbidity, and economic costs.Am J Med. 2002; 113: 5S-13S
- Early antibiotic treatment for pediatric febrile urinary tract infection and renal scarring.JAMA Pediatr. 2016; 170: 848-854
- Phenazopyridine hydrochloride: the use and abuse of an old standby for UTI.Urol Nurs. 2004; 24: 207-209
- Acquired methemoglobinemia and hemolytic anemia after usual doses of phenazopyridine.Drug Intell Clin Pharm. 1982; 16: 157-159
- Hypersensitivity hepatitis due to phenazopyridine hydrochloride.N Engl J Med. 1972; 286: 1090-1091
- Pharmacological studies on the mode of action of flavoxate.Arch Int Pharmacodyn Ther. 1984; 268: 301-302
- Clinical comparison of flavoxate and phenazopyridine.Urology. 1975; 5: 612-615
- Evaluation of symptom checkers for self-diagnosis and triage: audit study.BMJ. 2015; 531: h3480
- Best over the counter bladder infection treatment.([Accessed November 28, 2016])
Article Info
Publication History
Published online: November 30, 2016
Accepted:
November 28,
2016
Received in revised form:
November 28,
2016
Received:
November 15,
2016
Identification
Copyright
© 2016 Elsevier Inc. All rights reserved.
