Heart disease is one of the leading causes of death in the United States. With the
increase in substance abuse, the incidence of acute myocardial infarction (MI) in
younger population has been on the rise. Traditionally, cocaine has been blamed for
acute MI; however, recently, there have been more incidences of marijuana as an inciting
factor. We present a case of marijuana-induced acute MI and discuss the proposed mechanism.
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References
- Prevalence of marijuana use disorders in the United States: 1991-1992 and 2001-2002.JAMA. 2004; 291: 2114-2121
- Prospective multicenter evaluation of cocaine-associated chest pain. Cocaine Associated Chest Pain (COCHPA) Study Group.Acad Emerg Med. 1994; 1: 330-339
- Triggering myocardial infarction by marijuana.Circulation. 2001; 103: 2805-2809
- ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice.Am J Physiol Heart Circ Physiol. 2009;
- Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy.Nat Med. 2005; 11: 214-222
- Sildenafil-associated coronary thrombosis in a patient with angiographically normal coronary arteries: a case report with review of literature.Am J Ther. 2006; 13: 378-384
- Myocardial infarction following the combined recreational use of Viagra and cannabis.Clin Cardiol. 2002; 25: 133-134
- Oxidation of the endogenous cannabinoid arachidonoyl ethanolamide by the cytochrome P450 monooxygenases: physiological and pharmacological implications.Pharmacol Rev. 2010; 62: 136-154
Article Info
Publication History
Published online: February 10, 2012
Accepted:
December 13,
2011
Received:
December 10,
2011
Identification
Copyright
© 2012 Elsevier Inc. Published by Elsevier Inc. All rights reserved.