We thank Katoh et al [
[1]
] for their interesting article. The authors reported takotsubo syndrome associated
with hypoglycemia. We are also interested in takotsubo syndrome and recently reviewed
this condition and its association. We found an interesting topic regarding association
between takotsubo cardiomyopathy and thrombocytopenia. We would like to discuss the
possible causes of thrombocytopenia in patients with takotsubo syndrome. Although
there is no clear explanation for why patients with takotsubo syndrome can present
with thrombocytopenia, there have been reports of this acute cardiomyopathy and thrombocytopenia
related to thrombotic thrombocytopenic purpura [
[2]
] and seizure [
[3]
] in the literature. Renal insufficiency, fever, hemolytic anemia, or seizure in patients
with takotsubo cardiomyopathy should raise the suspicion of thrombotic thrombocytopenic
purpura.To read this article in full you will need to make a payment
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References
- Takotsubo cardiomyopathy associated with hypoglycemia: inverted takotsubo contractile pattern.Am J Emerg Med. 2012; 30: 2098.e1-2098.e3
- Acute cardiomyopathy in a patient with thrombotic thrombocytopenic purpura.Am J Med. 2010; 123: e3-e4
- Seizure-induced Takotsubo cardiomyopathy and thrombocytopenia.Eur J Neurol. 2011; 18: e68-e69
Article Info
Publication History
Published online: January 24, 2013
Accepted:
December 12,
2012
Received:
December 9,
2012
Footnotes
☆Conflict of interest statement for all authors: We do not have any financial or nonfinancial potential conflicts of interest.
☆☆Authors' contributions: All authors had access to the data and a role in writing the manuscript.
Identification
Copyright
Published by Elsevier Inc.
