Anaerobiospirillum succiniciproducens is rarely associated with bacteremia but results in significant mortality. Almost
all reported bacteremia cases have occurred in immunocompromised hosts, such as those
with alcoholic liver disease, atherosclerosis, recent surgery, malignancies, or acquired
immunodeficiency syndrome. We describe here, to our knowledge, the first clinical
evidence for A succiniciproducens bacteremia in a healthy man. A 61-year-old man had fallen from a roof and was admitted
to our emergency department with severe left flank pain without an external wound.
He was given transcatheter arterial embolization for the left kidney injury on the
same day, and his condition stabilized. Four days after admission, he had fever without
gastrointestinal signs and symptoms. Spiral-shaped, gram-negative anaerobic bacteria
were isolated from 2 sets of blood cultures, and the oxidase and catalase test results
were negative. The isolated bacteria were different from the Campylobacter spp. On the next day, the bacteria were confirmed as A succiniciproducens by 16S rRNA sequencing. The patient responded to sulbactam/ampicillin. On day 13,
the patient was discharged with a 7-day prescription for oral amoxicillin/clavulanate.
Six months after admission, the patient was free of recurrent infection. A succiniciproducens bacteremia can occur in healthy adults. When large gram-negative spiral-shaped bacteria
are detected, this bacterial species should be considered and differentiated from
the Campylobacter spp because A succiniciproducens is often resistant to macrolide antibiotics.
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References
- Description of a medium for isolating Anaerobiospirillum spp., a possible cause of zoonotic disease, from diarrheal feces and blood of humans and use of the medium in a survey of human, canine, and feline feces.J Clin Microbiol. 1990; 28: 1380-1384
- Occurrence and species level diagnostics of Campylobacter spp., enteric Helicobacter spp. and Anaerobiospirillum spp. in healthy and diarrheic dogs and cats.Vet Microbiol. 2008; 129: 304-314
- Anaerobiospirillum thomasii sp. nov., an anaerobic spiral bacterium isolated from the feces of cats and dogs and from diarrheal feces of humans, and emendation of the genus Anaerobiospirillum.Int J Syst Bacteriol. 1997; 47: 381-384
- Bloodstream infection with Anaerobiospirillum succiniciproducens: a potentially lethal infection.South Med J. 2011; 104: 205-214
- Anaerobiospirillum succiniciproducens bacteraemia in a patient with acute lymphoblastic leukaemia.J Med Microbiol. 2009; 58: 142-143
- Anaerobiospirillum succiniciproducens septicemia.Rinsho Byori. 2007; 55: 930-935
- Three cases of Anaerobiospirillum succiniciproducens bacteremia confirmed by 16S rRNA gene sequencing.J Clin Microbiol. 1998; 36: 1209-1213
- Bacteremia with Anaerobiospirillum succiniciproducens.Rev Infect Dis. 1987; 9: 737-742
- Ultrastructural characterization of Anaerobiospirillum succiniciproducens and its differentiation from Campylobacter species.FEMS Microbiol Lett. 1999; 170: 83-88
- First report of treatment of Anaerobiospirillum succiniciproducens bloodstream infection with levofloxacin.J Clin Microbiol. 2010; 48: 1970-1973
- Anaerobiospirillum succiniciproducens septicaemia: important aspects of diagnosis and management.J Infect. 1998; 37: 68-70
Article Info
Publication History
Published online: December 20, 2013
Accepted:
December 11,
2013
Received:
December 6,
2013
Footnotes
☆Financial disclosure: The authors declare no inflict of interest.
☆☆Disclosure of conflicts of interest: None of the authors has any conflict of interest to disclose.
★Consent: Written informed consent was obtained from the patient for publication of this case report and any accompanying images.
★★Authors' contributions: TI and AM contributed to patient management. JM performed the microbiological culture and identification. RI drafted the initial manuscript. SN and NY critically reviewed the manuscript. All of the authors have provided written consent for publication.
Identification
Copyright
© 2014 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
