Previous research has shown that cardiac dysfunction in severe sepsis worsens outcomes
and increases mortality
[
[1]
]. Dogan et al.
[
[2]
] in their correspondence point out that further evidence is still necessary to prove
that elevated cardiac biomarkers, specifically cardiac troponin I (cTnI) and brain
natriuretic (BNP) levels, are associated with higher mortality for patients with severe
sepsis. As requested, we conducted an analysis using the same study sample that was
used to evaluate the Mortality in Severe Sepsis in the Emergency Department scoring
method, which identified several clinical factors associated with higher in-hospital
mortality
[
[3]
]. For statistical analysis, the Student t test was used to determine an association between cardiac biomarkers, ejection fraction
(EF%), and in-hospital mortality.To read this article in full you will need to make a payment
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References
- Plasma brain natriuretic peptide and troponin levels in severe sepsis and septic shock: relationships with systolic myocardial dysfunction and intensive care unit mortality.J Intensive Care Med. 2014; 29: 229-237
- Predictors of Mortality in Severe Sepsis.2016 ([in press])
- Usefulness of the Mortality in Severe Sepsis In The Emergency Department score in an urban tertiary care hospital.Am J Emerg Med. 2016; 34: 1117-1120
Article Info
Publication History
Published online: June 30, 2016
Accepted:
June 28,
2016
Received:
June 27,
2016
Footnotes
☆Funding: None.
☆☆Presentations: None.
Identification
Copyright
© 2016 Elsevier Inc. All rights reserved.
