Atypical presentation of gangrenous cholecystitis: A case series

Published:August 17, 2018DOI:


      Gangrenous cholecystitis (GC) is a serious complication of acute cholecystitis that has been associated with increased morbidity. Patient with GC can present with a wide variety of non-specific clinical, laboratory, and imaging characteristics, making the diagnosis challenging. This disease requires emergent treatment, which is why a quick and reliable diagnosis is essential for the wellbeing of the patient. The authors herein present a case of GC in a patient whose initial complaint was intractable hiccups, and provide a thorough review of the literature of cases of GC with atypical presentations.


      mm Hg (millimeter of mercury), mg/dl (milligrams per deciliter), /cu∙mm (per one cubic millimeter), ×103 (thousand), Afib (atrial fibrillation), ALT (alanine transaminase), AS (aortic stenosis), AST (aspartate transaminase), C (cholecystitis), CA (cancer), CBD (common bile duct), CKD (chronic kidney disease), CRP (C-reactive protein), CT (computed topography), DMII (diabetes mellitus II), ED (emergency department), ERCP (endoscopic retrograde cholangiopancreatography), GC (gangrenous cholecystitis), GERD (gastroesophageal reflux disease), GGT (gamma-glutamyl transferase), HTN (hypertension), ILD (interstitial lung disease), IU/L (international units per liter), N/V (nausea and vomiting), O2 (oxygen), RUQ (right upper quadrant), SGOT (serum glutamic oxaloacetic transaminase), SGPT (serum glutamic pyruvic transaminase), SPS (statistical package for social sciences), T (temperature), WBC (white blood cell)


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