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Comments on GEDI vs. CVP goal-directed fluid resuscitation for COPD patients with septic shock: A randomized controlled trial

Published:March 01, 2019DOI:https://doi.org/10.1016/j.ajem.2019.02.041
      We have read the paper written by Jiangquan Yu et al. [

      Yu Jiangquan, Zheng Ruiqiang, Lin Hua, Chen Qihong, Shao Jun, Wang Daxin, GEDI vs. CVP goal-directed fluid resuscitation for COPD patients with septic shock: a randomized controlled trial, American Journal of Emergency Medicine (2016), doi: https://doi.org/10.1016/j.ajem.2016.10.015.

      ] with great interest. A study was conducted to investigate the clinical effects of the global end-diastolic volume index (GEDI)-oriented fluid resuscitation on chronic obstructive pulmonary disease (COPD) patients with septic shock, which resulted that the GEDI goal-directed fluid therapy did improve clinical effects, but it could not reduce the mortality rate. We appreciate the authors for their successful work. However, in order to avoid misinterpretation, some points need be further discussed.

      Abbreviations:

      GEDI (global end-diastolic volume index), CVP (central venous pressure), COPD (chronic obstructive pulmonary disease), PASS (power analysis and sample size)

      Keywords

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      References

      1. Yu Jiangquan, Zheng Ruiqiang, Lin Hua, Chen Qihong, Shao Jun, Wang Daxin, GEDI vs. CVP goal-directed fluid resuscitation for COPD patients with septic shock: a randomized controlled trial, American Journal of Emergency Medicine (2016), doi: https://doi.org/10.1016/j.ajem.2016.10.015.

      2. The ARISE Investigators and the ANZICS Clinical Trials Group. Goal-directed resuscitation for patients with early septic shock. N Engl J Med 371:1496–1506.

        • Machin D.
        • Campbell M.
        • Fayers P.
        • Pinol A.
        Sample size tables for clinical studies.
        2nd ed. Blackwell Science, Malden, MA1997
        • Zar Jerrold H.
        Biostatistical analysis.
        2nd ed. Prentice-Hall. Englewood Cliffs, New Jersey1984
        • Rhodes A.
        • Evans L.E.
        • Alhazzani W.
        • et al.
        Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016.[J].
        Intensive Care Med. 2017; 43: 1-74
        • Schmerzther Anasthesiol Intensivmed Notfallmed
        Feb. 2018; 53: 142-148