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Antibiotics with nasal packing—The authors reply

Published:March 11, 2019DOI:https://doi.org/10.1016/j.ajem.2019.03.022
      On behalf of my co-authors, and myself I would like to thank you for your interest in our study as well as your thoughtful questions. The purpose for our study was to compare infection rates of patients with and without prophylactic systemic antibiotics who had anterior packing for spontaneous epistaxis as well as examine the management practices of prescribing prophylactic antibiotics for these patients in the emergency department. In performing our literature search, we have found that prophylactic antibiotic prescribing practices vary among otolaryngologists mainly because there is a paucity of literature that supports a clear benefit to its use. Moreover, many of the studies that do exist, do not support the general use of prophylactic antibiotics for patients with nasal packing for spontaneous anterior epistaxis; however, these studies are insufficiently powered to make a definitive scientific conclusion.
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