N,N-Dimethyltryptamine (DMT) is a novel hallucinogen that acts on brain serotonin receptors
and produces a brief yet intense dream-like state with reported psycho-spiritual effects
[
[1]
]. DMT is growing in popularity as a recreational substance but limited knowledge
exists of its adverse effects [
[2]
]. We report the cases of two young male patients with no prior psychiatric history
who presented to an urban academic emergency department (ED) with psychotic symptoms
after consumption of DMT.Keywords
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References
- Ayahuasca: psychological and physiologic effects, pharmacology and potential uses in addiction and mental illness.Curr Neuropharmacol. 2019; 17: 108-128
- Dimethyltryptamine (DMT): prevalence, user characteristics and abuse liability in a large global sample.J Psychopharmacol. 2014; 28: 49-54
- Ayahuasca exposure: descriptive analysis of calls to US Poison Control Centers from 2005 to 2015.J Med Toxicol. 2017; 13: 245-248
- Recreational use of naturally occurring dimethyltryptamine—contributing to psychosis?.Aust N Z J Psychiatry. 2013; 47: 398-399
- Ayahuasca, dimethyltryptamine, and psychosis: a systematic review of human studies.Ther Adv Psychopharmacol. 2017; 7: 141-157
Article Info
Publication History
Published online: May 03, 2020
Accepted:
April 30,
2020
Received:
April 21,
2020
Identification
Copyright
© 2020 Elsevier Inc. All rights reserved.
