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Sleep deprivation hormesis: The shift that doesn't kill you makes you stronger

      Emergency medicine approximates a prehistoric human schedule. Our ancestors spent most of their time walking, socializing, relaxing, and conserving energy [
      • Pontzer H.
      • Wood B.M.
      • Raichlen D.A.
      Hunter-gatherers as models in public health.
      ]. When motivated, they could sprint away from a tiger or toward a mammoth. Humans fasted for hours or days, then consumed large amounts of food when they found a beehive or large mammal. Primitive humans faced a range of discomfort in their environments. Without gas-powered furnaces, car air conditioning and safe homes, they frequently felt cold, hot, and tired. By overcoming adversity, humans used acute stresses to become more resilient.
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