Abstract
Purpose
The purpose of this study was to investigate the clinical use of copeptin to evaluate
migraine attacks in the Emergency Department. An additional aim was to detect changes
in serum copeptin levels in migraine patients during attack and attack-free periods.
Methods
This prospective case–control study included 52 migraine patients and 51 healthy individuals
with similar demographic characteristics. Blood samples were collected from migraine
patients both in attack and attack-free periods.
Results
The mean copeptin levels in the patients group in the attack and attack-free periods
were 689.28 and 576.68 pg/ml, respectively, whereas they were 608.68 pg/ml in the
control group. There was a significant difference in the mean copeptin level in the
attack period and attack-free periods (p = 0.026). The sensitivity and specificity
of copeptin in detecting headache episodes in migraine patients were 58.8% and 60.7%,
respectively, at a cut-off value of 388.67 pg/ml.
Conclusion
This is the first study to investigate the diagnostic efficacy of serum copeptin levels
in migraine patients. Although the diagnostic efficacy of serum copeptin levels for
migraines was unsatisfactory, it could be helpful at management of migraine patients
in ED.
Keywords
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Article Info
Publication History
Published online: May 07, 2020
Accepted:
May 3,
2020
Received in revised form:
March 4,
2020
Received:
February 5,
2020
Footnotes
☆This work was performed in Medical Faculty of Suleyman Demirel University, Emergency Medicine Department.
☆☆This study has not been published or presented before and is not currently being considered for publication elsewhere.
Identification
Copyright
© 2020 Elsevier Inc. All rights reserved.
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- Corrigendum to “Clinical Use of Copeptin in Migraine Patients Admitted to the Emergency Department” [American Journal of Emergency Medicine, Volume 38, Issue 9, September 2020, P1910–1914]The American Journal of Emergency MedicineVol. 38Issue 12
