Abstract
Objective
Recently, the ACUTE HF score has been developed as a new tool for predicting short
and long term mortality in patients with acute heart failure (AHF). However, this.
score has not yet been validated externally. The present study aimed to investigate
the prognostic value of ACUTE HF score in a different patient cohort.
Methods
We retrospectively enrolled all consecutive adult patients hospitalized due to AHF
between January 2016 and January 2019. The ACUTE HF score is calculated by 7 different
variables including age, creatinine, non-invasive ventilation, history of stroke or
transient ischemic attack, left ventricular systolic function, mitral regurgitation
and history of hospitalization.The primary endpoint of the study was in-hospital mortality.
Results
A total of 418 AHF patients (mean age 70.2 ± 11.3 years, 52% male) were included,
and 26 (6.2%) patients died during the in-hospital course. Patients in the study were
divided into three groups according to ACUTE HF score: low-risk (<1.5, n = 210), intermediate-risk
(1.5–3, n = 50), and high-risk groups (>3, n = 158). The multivariate analysis showed
that the ACUTE HF score was an independent predictor of in-hospital mortality(OR:
2.15; 95% CI, 0.94–4.34; p < 0.001).
Conclusion
The ACUTE HF score was a useful prognostic score for the prediction of in-hospital
mortality in patients with AHF. Further validation studies in different regions of
the world and with different AHF populations are needed to determine its generalisability.
Keywords
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Article Info
Publication History
Published online: November 20, 2020
Accepted:
November 18,
2020
Received in revised form:
November 1,
2020
Received:
August 11,
2020
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2020 Elsevier Inc. All rights reserved.
