Abstract
We present a case of daily, large ingestions of soymilk that likely led to acute pancreatitis.
Soybean contains trypsin inhibitor that when ingested will reduce the activity of
trypsin in the intestine. A decrease in intestinal proteolytic activity removes the
negative feedback on the pancreatic acinar cells, leading to an inappropriate increase
in intrapancreatic trypsin secretion. When trypsin activation exceeds the capacity
of pancreatic secretory trypsin inhibitor, the subsequent cascade of events can lead
to acute pancreatitis.
Keywords
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Article Info
Publication History
Published online: January 27, 2021
Accepted:
January 22,
2021
Received in revised form:
January 14,
2021
Received:
January 12,
2021
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2021 Elsevier Inc. All rights reserved.
