Abstract
Aim
The aim of this study is to investigate whether abdominal compression cardiopulmonary
resuscitation (CPR) would result in similar survival rates and neurologic outcome
than chest compression CPR in a swine model of cardiac arrest.
Materials and methods
Forty Landrace/Large White piglets were randomized into 2 groups: group A (n = 20)
was resuscitated using chest compression CPR, and group B (n = 20) was resuscitated
with abdominal compression CPR. Ventricular fibrillation was induced with a pacemaker
catheter, and animals were left untreated for 8 minutes. Abdominal and chest compressions
were applied with a mechanical compressor. Defibrillation was then attempted.
Results
Neuron-specific enolase and S-100 levels were significantly higher in group B. Ten
animals survived for 24 hours in group A in contrast to only 3 animals in group B
(P < .05). Neurologic alertness score was worse in group B compared with group A.
Conclusion
Abdominal compression CPR does not improve survival and neurologic outcome in this
swine model of cardiac arrest and CPR.
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Article Info
Publication History
Published online: May 03, 2010
Accepted:
January 27,
2010
Received:
January 18,
2010
Identification
Copyright
© 2011 Elsevier Inc. Published by Elsevier Inc. All rights reserved.