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The intractable intra-abdominal hemorrhage with unknown etiology in a patient with severe hemophilia A

  • Kazuho Morichika
    Affiliations
    Division of Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology (Second Department of Medicine), Graduate School of Medicine, University of the Ryukyus, Nakagami, Okinawa, Japan
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  • Takeaki Tomoyose
    Affiliations
    Division of Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology (Second Department of Medicine), Graduate School of Medicine, University of the Ryukyus, Nakagami, Okinawa, Japan
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  • Yukiko Nishi
    Affiliations
    Division of Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology (Second Department of Medicine), Graduate School of Medicine, University of the Ryukyus, Nakagami, Okinawa, Japan
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  • Sawako Nakachi
    Affiliations
    Division of Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology (Second Department of Medicine), Graduate School of Medicine, University of the Ryukyus, Nakagami, Okinawa, Japan
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  • Takuya Fukushima
    Affiliations
    Laboratory of Hematoimmnology, School of Health Sciences, Faculty of Medicine, University of the Ryukyus, Nakagami, Okinawa, Japan
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  • Hiroaki Masuzaki
    Correspondence
    Corresponding author at: Division of Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology (Second Department of Medicine), Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara cho, Nakagami, Okinawa, Japan. Tel.: +81 98 895 1146; fax: +81 98 895 1415.
    Affiliations
    Division of Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology (Second Department of Medicine), Graduate School of Medicine, University of the Ryukyus, Nakagami, Okinawa, Japan
    Search for articles by this author
      Severe hemophilia patients are more likely to be complicated by intra-articular hemorrhage, subcutaneous hemorrhage, and intramascular hemorrhage. Spontaneous intra-abdominal hemorrhage is a rare fatal disease, which is an arterial bleeding of uncertain causes from vessel feeding arteries. In case the spontaneous intra-abdominal hemorrhage is complicated to severe hemophilia patients, the mortality rate increases considerably. We experienced a patient with severe hemophilia A, who made a full recovery from spontaneous intra-abdominal hemorrhagic shock by replacement therapy of coagulation factor VII, a noninvasive procedure.
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