The utility of bolus intravenous nicardipine for hypertensive emergencies in the ED

Stephanie N. Komura; Nadia I. Awad

doi:10.1016/j.ajem.2016.03.050

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The utility of bolus intravenous nicardipine for hypertensive emergencies in the ED☆

Stephanie N. Komura, PharmD

Department of Pharmacy, Robert Wood Johnson University Hospital, New Brunswick, NJ

Department of Pharmacy Practice and Administration, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ

Nadia I. Awad, PharmD, BCPS

Department of Pharmacy, Robert Wood Johnson University Hospital, New Brunswick, NJ

DOI: http://dx.doi.org/10.1016/j.ajem.2016.03.050

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Nicardipine is a commonly used agent for the management of hypertensive emergencies due to its predictable pharmacokinetic profile and ease of titration. There is documented use of nicardipine administered as an intravenous (IV) bolus dose in several settings, particularly in the anesthesia literature. We describe the first 2 documented cases of use of nicardipine administered as an IV bolus dose in the emergency department (ED) for hypertensive emergencies involving acute ischemic stroke and hemorrhagic stroke.

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☆Financial disclosures: The authors have no financial disclosures to report relevant to this manuscript.

The utility of bolus intravenous nicardipine for hypertensive emergencies in the ED☆

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