We thank Dr. Cerlik very much for his comments relating to our paper, ‘ST depression in lead aVL differentiates inferior ST elevation myocardial infarction from pericarditis.’ Our aim with this paper was to identify a sensitive and specific finding to differentiate inferior STEMI from pericarditis in the acute clinical context of the emergency department. We found that any ST depression in aVL was highly sensitive and specific in this setting, and is a very useful clinical tool to quickly identify patients who require immediate cardiac catheterization.