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Acute corrosive poisonings - Frequent cause for fatal outcome

  • Andon Chibishev
    Correspondence
    Corresponding author at: University Clinic for Toxicology and Urgent Internal Medicine, Boulevard “Vodnjanska 17”, Skopje, The Former Yugoslav Republic of Macedonia.
    Affiliations
    University Clinic for Toxicology and Urgent Internal Medicine, Skopje, The Former Yugoslav Republic of Macedonia

    University “Goce Delchev”, Medical Faculty, Shtip, The Former Yugoslav Republic of Macedonia

    University “Ss. Cyril and Methodius”, Medical Faculty, Skopje, The Former Yugoslav Republic of Macedonia
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  • Natasha Davceva
    Affiliations
    Institute of Forensic Medicine, Medical Faculty, University “Ss. Cyril and Methodius”, Skopje, The Former Yugoslav Republic of Macedonia
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  • Emilija Shikole
    Affiliations
    Institute for Pharmacology and Preclinical Toxicology, Medical Faculty, University “Ss. Cyril and Methodius”, Skopje, The Former Yugoslav Republic of Macedonia
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  • Cvetanka Bozinovska
    Affiliations
    University Clinic for Toxicology and Urgent Internal Medicine, Skopje, The Former Yugoslav Republic of Macedonia

    University “Ss. Cyril and Methodius”, Medical Faculty, Skopje, The Former Yugoslav Republic of Macedonia
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Published:February 09, 2018DOI:https://doi.org/10.1016/j.ajem.2018.02.010
      We are presenting you with a follow-up of our previously published study pertaining to acute corrosive intoxications, based on data collected over a ten-year period. Despite the efforts to decrease the incidence of acute corrosive intoxications through educational activities, media platforms and information brochures about the health risks from the ingestion and abuse of corrosive agents, these poisonings are still a serious medical and social issue with high morbidity and mortality rates. Our study showed that the occurrence of these poisonings was higher in populations of lower socioeconomic and health status, among which there were higher rates of suicide attempts, greater risk for long-term invalidity and even death. In most cases, the fatal outcome occurred during the first 96 h after the ingestion and was caused by esophageal or gastric perforation, laryngeal edema, or corrosive agent aspiration with tracheal necrosis, septic shock and multisystem organ failure [
      • Park K.S.
      Evaluation and management of caustic injuries from ingestion of acid or alkaline substances.
      ,
      • Byard R.W.
      Caustic ingestion-a forensic overview.
      ].
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