Abstract
Study objective
To investigate the frequency of Beers Criteria (BC) medication and opioid use in patients
age 65 years and older arriving in the Emergency Department.
Methods
We performed a retrospective observational study of a convenience sample of 400 patients,
age 65 years and older, arriving to and discharged solely from the Emergency Department.
We examined 400 sequential patient charts with visit dates April–July 2017, for the
presence of a Beers Criteria medication or opioid prescription. We also examined each
chart for nine specific chief complaints, including return visits and subsequent admissions.
Results
Of the 400 patients included in this study, 304 patients (76%; 95% confidence interval
[CI] 72% to 80%) had at least 1 prescription at the index ED visit for an “avoid”
or “use with caution” Beers Criteria medication. Of these patients, 194 (64%; 95%
CI 58% to 69%) had ≥2 Beers medication prescriptions and 122 patients (40%; 95% CI
35% to 46%) had ≥3 Beers medication prescriptions. We found no difference in the number
of patients with a chief complaint of interest between the BC medication list (28%)
and lacking a BC medication (29%) (p-value = 1). No patients returned in the next
7 days for a medication-related complaint.
Conclusion
The results of this study call into question the routine application of lists without
high-quality evidence to critique the prescribing of certain medications. Further
patient-oriented study of the relevance of the Beers Criteria list, especially in
light of the changed face of medication profiles and populations, is called for.
Keywords
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References
- Clinical consequences of polypharmacy in elderly.Expert Opin Drug Saf. 2014; 13: 57-65
- Explicit criteria for determining inappropriate medication use in nursing home residents.Arch Intern Med. 1991; 151: 1825-1832
- American Geriatrics Society updated Beers criteria for potentially inappropriate medication use in older adults.J Am Geriatr Soc. 2012; 60: 616-631
- American Geriatrics Society 2015 Beers criteria for potentially inappropriate medication use in older adults.J Am Geriatr Soc. 2015; 63: 2227-2246
- What is GRADE?.(from)https://bestpractice.bmj.com/info/us/toolkit/learn-ebm/what-is-grade/Date: 2019Date accessed: May 4, 2019
- Beers criteria and the ED: an adequate standard for inappropriate prescribing?.Am J Emerg Med. 2008; 26: 695-696
- Drug overdose death data.
- Opioid analgesics and the risk of fractures in older adults with arthritis.J Am Geriatr Soc. 2011; 59: 430-438
- Age-related pharmacokinetic and pharmacodynamic changes and related risk of adverse drug reactions.Curr Med Chem. 2010; 17: 571-584
- Aging biology and geriatric clinical pharmacology.Pharmacol Rev. 2004; 56: 163-184
- Potentially inappropriate prescribing of benzodiazepines for older adults and risk of falls during a hospital stay: a descriptive study.Can J Hosp Pharm. 2009; 62: 276-283
- National surveillance of emergency department visits for outpatient adverse drug events.JAMA. 2006; 296 (1858-6)
- Impact of inappropriate drug use on mortality and functional status in representative community dwelling elders.Med Care. 2002; 40: 166-176
- US emergency department visits for outpatient adverse drug events, 2013–2014.JAMA. 2016; 316: 2115-2125
- U.S. prescribing rate maps.(Accessed on July 27, 2018 from)
- Polypharmacy, adverse drug-related events, and potential adverse drug interactions in elderly patients presenting to an emergency department.Ann Emerg Med. 2001; 38: 666-671
- Polypharmacy and pain treatment.Wien Med Wochenschr. 2010; 160: 286-292
Article Info
Publication History
Published online: May 28, 2019
Accepted:
May 27,
2019
Received in revised form:
May 21,
2019
Received:
February 10,
2019
Identification
Copyright
© 2019 Published by Elsevier Inc.