The article by Fei Han et al in this issue of the Journal may be an important bit
of bench science. In a rodent model of global ischemia, they found that both the moderate-sized
(cyclic non-ribosomal peptide) pharmaceutical drug cyclosporine and therapeutic hypothermia
appear to blunt reperfusion related neuroinjury through similar mechanisms. Even more
intriguingly, Fei Han et al provide a first indication that the pharmaceutical efficacy
of cyclosporine and the physical efficacy of hypothermia may be somewhat additive.
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Article Info
Publication History
Published online: February 29, 2016
Accepted:
February 27,
2016
Received:
February 26,
2016
Footnotes
☆This editorial relates to the article published in this month's issue by Fei Han et al.
Identification
Copyright
© 2016 Elsevier Inc. All rights reserved.